In general, many international flights arrive in Miami (MIA). Not from all parts of the world you can reach other cities like Orlando or Tampa. But from Miami you can take a flight to connect with other cities in the state. As there are several buses that can take you to other places or if you prefer to rent a car you can do it at the airport (in high season, we recommend you make a reservation in advance).
If you have a car, this are the main roads or highways:
I-4, connects Tampa, Lakeland, Orlando and Daytona Beach.
I-10, it’s located to the North of the state, begins in Jacksonville and passes by Lake City, Tallahassee and Pensacola. It goes East-West.
I-75, in Florida begins close to Lake City and continues South passing by Gainesville, Ocala, part of it by Tampa and follows to Bradenton, Sarasota, Fort Myers and Naples. It later crosses the Everglades, and then goes East to Fort Lauderdale and finally to the South ending in Hialeah.
I-95, in Florida begins close to Jacksonville and continues by the East coast passing by Daytona Beach, Melbourne, Titusville, Palm Bay, Port Saint Lucie, West Palm Beach, Ft. Lauderdale and finally Miami.
If you take any of those routes to get to another city, you don’t have to pay tolls (only on the Everglades portion of I-75). And thanks to the fact that it passes through several cities, you can find many restaurants, fast food chains, stores and lodgings of various categories.
The state also has the Turnpike where you do have to pay tolls, but sometimes it is faster than other roads, especially if you go from Miami to Orlando. This freeway begins from the north on I-75 near Lake Panasoffkee (an open place for camping, fishing, hiking, and even hunting) and continues southeast through Orlando, Port Saint Lucie, Fort Lauderdale and Miami, to Homestead. Along this route, from time to time, you’ll find a rest area with public restrooms, small businesses, most of them offers free Wi-Fi and a food court. Since it is very touristy, you will also find maps and brochures of places of interest with discounts for hotels and attractions. If you travel with pets like dogs, you will find a little area for them to rest too.